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KMID : 0669519910010000078
Journal of Health Science - Yonsei University
1991 Volume.1 No. 0 p.78 ~ p.89
Prevalence of P-pili and Antimicrobial Resistance of Uropathogenic Escherichia coli


Abstract
A total of 131 Escherichia coli strains isolated from the urine of patients with various forms of urinary tract infection were analyzed for possession of P fimbriae, type 1 pili, production of hemolysin and antimicrobial resistance. The highest occurrence of P fimbriation(64.7%) and hemolysin production(35.3%) was found to be in patients with pyelonephritis, and these results might imply the significant correlation of the possession of P fimbriae with the virulence of uropathogenic E.coli
These E. coli strains were tested for the resistance to 10 antimicrobial agents. Generally, more than 50% of isolates showed antimicrobial resistance to ampicillin, cephalothin, streptomycin, kanamycin, tetracycline, and sulfamethoxazole. And no differences in the antimicrobial resistance of uropathogenic E. coli was observed between the P-imbriated and non-fimbriated strains, and in clinical diagnostic groups of pyelonephritis, cystitis and asymptomatic bacteriuria.
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